Scientists Uncover Genetic Factor Behind Gender Differences in Brain Aging

Gender differences in brain aging are explained by a genetic factor, according to scientists. Scientists have discovered a genetic factor that may explain why women experience slower brain aging and cognitive decline compared to men. Researchers in the United States found that a gene linked to the X chromosome plays a key role in brain rejuvenation, influencing gender-specific aging patterns. Women generally outlive men, but the biological reasons behind this difference have remained unclear. Both sexes inherit an X chromosome, but women have two, while men have one X and one Y chromosome. Previously, scientists believed that one of the two X chromosomes in females was largely inactive. However, this new study challenges that assumption. The findings reveal that the second X chromosome actively contributes to brain maintenance and repair in women. This could explain why women tend to experience slower cognitive decline and are less susceptible to certain neurodegenerative diseases. This discovery has major implications for understanding the role of genetics in aging. It also opens the door to potential gender-specific treatments for neurological conditions such as Alzheimer’s disease. These findings are an important step toward personalized medical approaches for brain health and aging, despite the need for additional research.